Research • Prevention • Human Health

Changing the trajectory of human health.

Supporting ambitious research aimed at preserving health, extending function and preventing disease before it takes hold.

Discover our work

Science with the potential to change what comes next.

The Sprott Institute for Health Research supports prevention-focused research where emerging science, human biology and clinical translation meet.

Focused on the years before disease becomes inevitable.

01

Brain health

Understanding how metabolism, nutrition and physiology may help preserve cognition and reduce the risk of neurodegenerative disease.

02

Metabolic health

Exploring the relationship between energy metabolism, resilience and the maintenance of human function across the lifespan.

03

Healthy aging

Supporting research that aims not simply to extend life, but to preserve strength, cognition, independence and quality of life.

04

Human translation

Helping promising ideas move beyond theory and into carefully designed human studies capable of answering meaningful clinical questions.

SPARCUS

SPARCUS is an initiative focused on metabolic brain health and the prevention of Alzheimer’s disease.

In collaboration with researchers and institutions, the program is examining whether strategies that improve brain energy metabolism — including ketogenic approaches and ketone-based therapeutics — can help preserve cognition and alter the course of neurodegenerative disease.

Metabolic brain health

From treating disease
to preserving health.

A shift in emphasis from intervention after decline toward prevention before it begins.

Bring the right people to the right questions.

Important breakthroughs rarely belong to a single discipline. The Institute is designed to encourage collaboration among scientists, clinicians, universities and research partners around questions with the potential for meaningful human impact.

01 Prioritize prevention and preservation of function.
02 Support rigorous human and translational research.
03 Encourage collaboration across scientific disciplines.
04 Back ideas capable of producing measurable human benefit.

The work is underway.

This website is currently being developed. More information about our research initiatives, collaborators, funding programs and upcoming projects will be published shortly.